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Frequently Asked Questions
Explore our Frequently Asked Questions to gain comprehensive knowledge about Ubiquinol CoQ10. Learn how Kaneka Ubiquinol® can effectively contribute to your overall well-being.
(Coenzyme Q10) is a naturally occurring antioxidant in the body. It has two forms: the fully oxidized form (ubiquinone) and the active antioxidant form (ubiquinol) — both are important for generating cellular energy in the electron transport chain (ETC). When ubiquinone receives two electrons from antioxidants, its structure changes, and it becomes ubiquinol. When ubiquinol gives up its electrons to a free radical, it reverts back to being CoQ10. The constant switching back and forth between ubiquinone and ubiquinol supports cellular energy production, which powers many other biological processes and overall health. You can learn more about this important molecule here: Ubiquinol vs Ubiquinone: Examining the Key Differences.
Commonly understood as “the powerhouse of the cell,” the mitochondria are crucial to whole-body health, but they’re more than powerhouses. Recent research has shown that mitochondria are responsible for managing, repairing, and protecting the intricate processes that maintain cellular health, making them more like the “CEO of the cell.” Understanding the value of mitochondria is important for understanding how Kaneka Ubiquinol® supports overall health. Review our Mitochondria Explained: Definitions to Know About the CEO of the Cell blog.
Ubiquinol is a powerful antioxidant, helping protect cells from the potentially harmful effects of free radicals and oxidative stress. These free radicals, generated during the body’s energy production process, have the potential to damage cells, proteins, and even DNA. A Kaneka Ubiquinol® supplement can actively support cellular energy production and promote cardiovascular health, healthy aging, cellular wellness, and overall well-being.
CoQ10’s two forms are equally important for generating cellular energy: the oxidized form (ubiquinone) and the active antioxidant form (ubiquinol). In healthy adults, 95% or more of the total CoQ10 in the blood is in the ubiquinol form. While your body naturally converts ubiquinone into ubiquinol, this process slows down after age 40. This is why taking a Kaneka Ubiquinol® supplement can be especially beneficial because it is already in the antioxidant form, so you can skip the conversion process and it can start protecting cells from free radical damage right away. Yet, a Kaneka Ubiquinol® supplement isn’t only effective for people over 40: Ubiquinol promotes cellular energy and offers a variety of health benefits at all adult life stages, like promoting preconception health, heart health, healthy aging, and much more.
Your body naturally produces ubiquinone, which is converted by the body into ubiquinol. Naturally occurring ubiquinol is found in every cell of the body, including the heart and brain. It’s essential for overall health, as it promotes cellular energy production and mitochondrial health — both of which are important for healthy organ and muscle function, healthy aging, and more.
Kaneka Ubiquinol® supports cardiovascular wellness, but there are many reasons people take this supplement, as its benefits go far beyond heart health: Ubiquinol works from the inside out, starting in the core of your cells to power your mitochondria, the “energy engines” of your body. Taking a Kaneka Ubiquinol® supplement promotes foundational processes like cellular energy production and cellular maintenance, as well as whole-body wellness. For those with specific health goals, it supports heart health, healthy aging, menopausal support, preconception health, and exercise resilience during and after strenuous or high-altitude workouts. Plus, no conversion is necessary to perform its antioxidant functions, as a Kaneka Ubiquinol® supplement is two times more bioavailable than a conventional CoQ10 supplement.
Supplementing with Kaneka Ubiquinol® can benefit adults of all ages. Your body’s ability to convert ubiquinone slows down around age 40, and while the ubiquinol form of CoQ10 is naturally present in some foods, it is difficult to consume meaningful levels of ubiquinol through the ordinary diet – particularly as you age. In your 20s and 30s, ubiquinol supplementation can support preconception health, help your body adapt to rigorous exercise, and promote long-term well-being. In your 40s and 50s and older, particularly as you become more concerned about healthy aging, Kaneka Ubiquinol® can especially support heart health, the menopausal phase, healthy aging, and CoQ10 depletion (if you take statin medications). At any age, high-quality Kaneka Ubiquinol® acts as your lifelong wellness ally.
A Kaneka Ubiquinol® supplement is bioidentical to the ubiquinol made naturally in the body. It assists with cellular energy production and, as an antioxidant, provides protection from free radical damage which, if left unchecked, can lead to a condition called “oxidative stress.”
Ubiquinol works at the cellular level, transferring electrons in the all-important production of energy within the cells of the body, including the heart (which requires significant amounts of cellular energy to maintain proper function). It protects cells from oxidative stress and promotes healthy aging, maintains cellular wellness during and after exercise, and can support menopause and preconception health.
A Kaneka Ubiquinol® supplement is not for one type of person: it’s for everyone. Its antioxidant properties mean it contributes to overall health in many ways:
- Promotes cellular energy and mitochondrial health
- Through its antioxidant properties, keeps free radical levels at bay, which protects against oxidative stress
- Supports healthy aging
- Promotes preconception health for men and women
- Promotes menopausal health
- Helps maintain heart health and function
- Replenishes ubiquinol levels depleted from cholesterol-lowering statin medications
- Promotes muscle health for an active lifestyle at any age
- Supports cellular wellness and physical performance during rigorous exercise
No. Kaneka Ubiquinol® is a dietary ingredient contained in more than 200 dietary supplement brands and is available in retail stores and on e-commerce sites. Kaneka Ubiquinol® is the subject of 85+ published research studies. It’s been available to consumers in the U.S. for over 17 years.
For over 50 years, Kaneka Corporation has led the way in global ubiquinol and ubiquinone research, driving innovation and improving the quality of our products to help people everywhere live healthier lives. More than 85 human clinical studies have been conducted using Kaneka Ubiquinol®, and it has been shown to support healthy aging, heart health, and preconception health.
You can read more about ubiquinol CoQ10 research findings here. Kaneka Nutrients leads the U.S. ubiquinol market by exposing misleading claims and counterfeit products through a market surveillance and testing program, so you can make informed choices about Kaneka Ubiquinol® supplements. Review the initial results of our testing program that identifies mislabeled products.
Statin medicines work by inhibiting the body’s production of cholesterol. Because CoQ10 is formed via the same pathway as cholesterol, people who take a statin may have reduced levels of both ubiquinone CoQ10 and ubiquinol, the active antioxidant form of CoQ10.
Taking a ubiquinol supplement helps replenish reduced levels of CoQ10 associated with statin use. Because Kaneka Ubiquinol® is more readily absorbable by the body than conventional CoQ10 supplements, Kaneka Ubiquinol® supplements are the preferred form of CoQ10 for statin drug users.
This article explains more about ubiquinol CoQ10 and cholesterol-lowering statin medicines. Please check with your doctor before starting to take any supplement.
Ubiquinol helps keep your cells and body functioning well. It also protects against free radicals and oxidative stress, offering daily antioxidant support for adults at all life stages. When you take a conventional CoQ10 supplement, your body must convert it into ubiquinol – the active antioxidant form of CoQ10 – in order for it to act as an antioxidant.
The conversion of CoQ10 to ubiquinol becomes less efficient as we age, however, which is why taking a Kaneka Ubiquinol® supplement is especially beneficial, especially for adults in their 30s, 40s, 50s, and beyond – whether you are concerned about reproductive health, exercise performance, cardiovascular health, or healthy aging.
There are over 200 retail brands that use Kaneka Ubiquinol® in their ubiquinol supplements, which can be found in thousands of health food stores, pharmacies, and grocers. Retailers that specialize in vitamins and supplements will generally offer a wider selection of supplements containing Kaneka Ubiquinol®.
You can use our Store Locator to find a retailer of supplements containing Kaneka Ubiquinol® close to your home. You can read our free Ubiquinol Buyer’s Guide to learn about the best way to purchase Kaneka Ubiquinol®.
In general, for healthy adults, 100mg ubiquinol is recommended per day. However, individual requirements vary, and depending on your medical history, health status, and lifestyle, your healthcare provider may advise starting with a higher dose – typically 200mg daily. A blood test can measure your CoQ10 levels to see if you are deficient in CoQ10 and guide ubiquinol dosage recommendations. Talk to your doctor about testing your CoQ10 levels to determine the most suitable dosage regimen for you.
In clinical studies, ubiquinol has commonly been used at 100 mg to 200 mg per day. Older adults and people with certain health concerns are sometimes guided toward the higher end. Your provider can help you find the right amount for your needs. See also: Clinical Studies on Ubiquinol
Ubiquinol can be taken at any time of the day, and many people take their ubiquinol CoQ10 supplement each morning with breakfast. If you take more than one ubiquinol capsule each day, consider taking them at different times — for example, take one capsule in the morning and another in the afternoon. If you have trouble falling asleep, avoid taking ubiquinol CoQ10 in the evening.
Most multivitamins do not contain ubiquinol. In addition, unlike many other nutrients, ubiquinol CoQ10 is fat-soluble (rather than water-soluble). This means it is best to be delivered in a soft gel with a fat such as sunflower, canola, or olive oil. Taking a Kaneka Ubiquinol® supplement with food is not necessary, but can be beneficial to ease absorption.
Since 1977, Kaneka Corporation, Kaneka Nutrients’ parent company, has commercially manufactured yeast-fermented and naturally-derived ubiquinone CoQ10 — a CoQ10 that is bioidentical to the ubiquinone produced naturally in the body.
After 10 years of initial research, Kaneka Corporation developed the world’s first and only ubiquinol CoQ10 commercially available for use in supplements. Kaneka Ubiquinol® has been shown to support heart health, healthy aging, cellular and mitochondrial health, preconception health, and more — and researchers continue to explore additional health benefits.
Kaneka Nutrients makes ubiquinol CoQ10 in the United States. We sell the nutrient to supplement companies that, in turn, use the ingredient in their own brand of ubiquinol supplement products. When you purchase a ubiquinol supplement, look for the Kaneka Quality Seal.
Ubiquinol products made with Kaneka Ubiquinol® earn the Kaneka Quality Seal. Finding this seal on a ubiquinol supplement bottle means the brand is relying on Kaneka for an ingredient manufactured according to exceptional quality standards.
The Kaneka Quality Seal is backed by more than 30 years of history within the CoQ10 market. It is also backed by a state-of-the-art production facility in Houston, where nutritional ingredients are made following a stringent quality assurance program based on the principles of “Kaizen” — the Japanese philosophy of continuous improvement.
Look for the Kaneka Quality Seal on your favorite brand of ubiquinol supplement.
Yes. The ubiquinol form of CoQ10 can be obtained from certain foods such as chicken, oily fish, whole grains, peanuts, spinach, avocados, olive oil, and some other foods. However, the amount of ubiquinol found in these foods is relatively small.
To get 100 mg of ubiquinol CoQ10, for example, you would have to eat 50 cups of spinach or more than three pounds of peanuts. In addition, when food is cooked, some or all of the ubiquinol contained within it can convert back to the oxidized ubiquinone form of CoQ10. This form of CoQ10 must be converted back to ubiquinol before it can perform its antioxidant functions.
For more information, read this article on foods that contain ubiquinol.
The ubiquinol form of CoQ10 is directly associated with over 95% of the body’s cellular energy production, but it will not give you a sudden boost of energy as one would expect to feel from the consumption of a beverage containing caffeine. When it comes to how Kaneka Ubiquinol® can support physical performance during rigorous workouts, it can support energy metabolism during exercise. Yet, it will not give you a sudden feeling of energy. Read this article about how ubiquinol promotes cellular energy and supports healthy aging for more information.
The cellular energy production associated with ubiquinol supports the body by providing cellular energy essential for your heart and other organs, mitochondrial wellness, healthy aging, exercise resilience, and more.
Kaneka Ubiquinol® can be safely taken with most prescription medications, but if you are taking any medication, talk to your doctor before starting a dietary supplement containing Kaneka Ubiquinol® .
Kaneka Ubiquinol® has been shown to be very well tolerated and has a well-established safety profile that supports its daily use. Its numerous health benefits make it a valuable addition to your wellness routine. For personalized recommendations on dosage and suitability, always consult with your doctor or licensed healthcare provider.