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There are a number of prescription and over-the-counter medications that can deplete your body's natural reserves of coenzyme Q10 (CoQ10) and ubiquinol. It is nearly impossible to replenish this nutrient through diet alone. Today, it's easy to find Kaneka Ubiquinol in supplement form. There are many high-quality brands sold in health food stores and pharmacies nationwide. Our Buyer's Guide has valuable information about what to look for when choosing a Kaneka Ubiquinol supplement. Be sure to ask your doctor about possible side effects if a health care provider recommends or prescribes any of the following drugs: (Reprinted with permission from Suzy Cohen's Drug Muggers)

Acid Blockers

Cimetidine (Tagamet)
Esomeprazole (Nexium)
Famotidine (Pepcid and Pepcid Complete)
Lansoprazole (Prevacid 24HR)
Nizatidine (Axid)
Omeprazole (Prilosec OTC)
Pantoprazole (Protonix)
Rabeprazole (Aciphex)
Ranitidine (Zantac)

Allergy Drugs

Promethazine (Phenergan)


Aluminum and magnesium hydroxide (Maalox, Mylanta)
Aluminum carbonate gel (Basaljel)
Aluminum hydroxide (Amphojel, AlternaGEL)
Calcium carbonate (Rolaids, Titralac, Tums)
Magnesium hydroxide (Phillips' Milk of Magnesia)
Sodium bicarbonate (Alka-Seltzer, baking soda)


Propafenone (Rythmol)
Sotalol (Betapace)

Antibiotics (a few examples)

Amoxicillin (Amoxil)
Azithromycin (Z-Pak)
Cefaclor (Ceclor)
Cefdinir (Omnicef)
Cephalexin (Keflex)
Ciprofloxacin (Cipro)
Clarithromycin (Biaxin)
Doxycycline (Doryx)
Erythromycin (E.E.S.)
Levofloxacin (Levaquin)
Minocycline (Minocin)
Sulfamethoxazole and trimethoprim (Septra, Bactrim)
Tetracycline (Sumycin)

Antidepressants, Tricyclic

Amitriptyline (Elavil)
Amoxapine (Asendin)
Clomipramine (Anafranil)
Desipramine (Norpramin)
Doxepin (Sinequan)
Imipramine (Tofranil)
Nortriptyline (Pamelor)
Protriptyline (Vivactil)

Blood Thinners

Warfarin (Coumadin) (Talk to your doctor first, but ubiquinone may slightly reduce the effectiveness of this drug, so a higher dose may be needed. Taking Ubiquinol still outweighs not taking it.)

Blood Pressure Drugs

Labetalol (Normodyne, Trandate)
Methyldopa (Aldomet)

ACE Inhibitors

Enalapril (Vasotec) (Ubiquinone enhances this drug's effect)

Angiotensin II Receptor Antagonists

Candesartan and HCTZ (Atacand HCT)
Telmisartan and HCTZ (Micardis HCT)


Acebutolol (Sectral)
Atenolol (Tenormin)
Betaxolol (Kerlone)
Bisoprolol (Zebeta, Ziac, Cardicor)
Carvedilol (Coreg)
Metoprolol (Lopressor and Toprol XL) (Ubiquinone enhances the benefits of this particular beta-blocker)
Nadolol (Corgard)
Propranolol (Inderal)
Timolol (Timoptic eye drops)

Centrally acting alpha-agonists hypotensive agents

Clonidine (Catapres)

Diuretic, sulfonamide

HCTZ or hydrochlorothiazide (Dyazide, Maxzide, Avapro HCT, Hyzaar, Micardis HCT and dozens more)
Indapamide (Lozol)
Moexipril and HCTZ (Univasc)

Diuretics, thiazide

Chlorothiazide (Diuril)
Hydrochlorothiazide or HCTZ (Hydrodiuril)
Methyclothiazide (Enduron)
Metolazone (Zaroxolyn)
Any combination drug that contains HCTZ or hyrdochlorothiazide (dozens of drugs contain this)

Cancer Drugs

Doxorubicin (Adriamycin) (Pre-treating yourself with Ubiquinol can help reduce damage to the heart from this chemotherapy drug.)

Cholesterol Reducers (Fibrates)

Fenofibrate (Tricor)
Gemfibrozil (Lopid)

Cholesterol Reducers (Statins)

Atorvastatin (Lipitor, Advicor)
Fluvastatin (Lescol)
Lovastatin (Mevacor, Altocor, Altoprev)
Pitavastatin (Livalo, Pitava)
Pravastatin (Pravochol, Lipostat, Selektine)
Rosuvastatin (Crestor)
Simvastatin (Zocor, Lipex)
Simvastatin and ezetimibe (Vytorin)
Simvastatin and niacin (Simcor)

Diabetes Medications

Acetohexamide (Dymelor)
Chlorpropamide (Diabinese)
Glimepiride (Amaryl)
Glipizide (Glucotrol)
Glyburide (Diabeta, Glynase, Micronase)
Glyburide and metformin (Glucovance)
Metformin (Fortamet, Glucophage, Glucophage, Glucophage XR, Glumetza, Riomet)
Metformin and sitagliptin (Janumet)
Pioglitazone (Actos)
Repaglinide (Prandin)
Rosiglitazone (Avandia)
Tolazamide (Tolinase)
Tolbutamide (Orinase)

HIV Drugs (Pyschiatric Drugs)

Chlorpromazine (Thorazine)
Droperidol (Inapsine)
Fluphenazine (Prolixin)
Haloperidol (Haldol)
Thioridazine (Mellaril)