What Role Does Ubiquinol Play In My Body And Overall Health?

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Our bodies naturally produce the Ubiquinol form of CoQ10. This nutrient is involved in 95% of your body’s cellular energy production, which helps your heart, lung, and other organs function properly.1, 2, 3

Ubiquinol promotes heart health by helping to provide your heart the fuel it needs to contract, relax, and maintain its cellular structure.

Ubiquinol is also an antioxidant, which protects your cells from oxidative stress.4, 5, 6 Ubiquinol neutralizes free radicals, which, when left unchecked, can damage healthy cells in the body.7

If you’re over 40 or taking a statin, your body makes less of this vital nutrient.8, 9, 10 To protect your cells and help support your heart and other organs function properly, consider taking a Ubiquinol supplement.11, 12 Learn more by visiting ubiquinol.com or asking your doctor about the benefits of this heart-healthy supplement.

Written by:

Risa Schulman

Ph.D

Risa Schulman, Ph.D. took her lifelong love of science, people and the fulfillment of potential to create a multifaceted career in R&D, business, health and wellness, and empowering individuals. 

References

 

1Tang PH, Miles MV, DeGrauw A, Hershey A, Pesce A. HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma. Clin Chem. 2001 Feb;47(2):256-65.

2Yamashita S, Yamamoto Y. Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress. Anal Biochem. 1997 Jul 15;250(1):66-73.

3Aberg F, Appelkvist EL, Dallner G, Ernster L. Distribution and redox state of ubiquinones in rat and human tissues. Arch Biochem Biophys. 1992 Jun;295(2):230-4

4Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007 Sep;37(1):31-7.

5Ernster L, Forsmark-Andrée P. Ubiquinol: an endogenous antioxidant in aerobic organisms. Clin Investig. 1993;71(8 Suppl):S60-5.

6Frei B, Kim MC, Ames BN. Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83.

7Sabbatinelli J, Orlando P, Galeazzi R, Silvestri S, Cirilli I, Marcheggiani F, Dludla PV, Giuliani A, Bonfigli AR, Mazzanti L, Olivieri F, Antonicelli R, Tiano L. Ubiquinol ameliorates endothelial dysfunction in subjects with mild-to-moderate dyslipidemia: A randomized clinical trial. Nutrients. 2020 Apr 15;12(4):1098.

8Langsjoen PH, Langsjoen AM. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors. 2008;32(1-4):119-28.

9Niklowitz P, Onur S, Fischer A, Laudes M, Palussen M, Menke T, Döring F. Coenzyme Q10 serum concentration and redox status in European adults: influence of age, sex, and lipoprotein concentration. J Clin Biochem Nutr. 2016 Jan. Online publication.

10 Wada H, Goto H, Hagiwara S, Yamamoto Y. Redox status of coenzyme Q10 is associated with chronological age. J Am Geriatr Soc. 2007 Jul;55(7):1141-2.

11Zlatohlavek L, Vrablik M, Grauova B, Motykova E, Ceska R. The effect of coenzyme Q10 in statin myopathy. Neuro Endocrinol Lett. 2012;33 Suppl 2:98-101.

12 Kinoshita T, Maruyama K, Tanigawa T. The effects of long term Ubiquinol intake on improving the quality of life in community residents. Functional Foods in Health and Disease. 2016 6(1):16-32.

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